Are Brain Cells Degenerated During an Epileptic Seizure

How Do New Brain Cells Develop?

For a considerable amount of time, conventional wisdom has maintained that we are born with all the brain cells we will ever have, that we cannot develop additional brain cells as adults, and that if those gray cells die, they are permanently lost.
This idea was supported, at least in part, by the observation that as we age, some motor (movement) and cognitive (thinking) abilities deteriorate. But does this imply that once we reach a certain age, everything goes south and we have to wait for the inevitable decline?
According to current studies, neurogenesis may persist into adulthood in some brain regions even after birth.

Quick Overview

Even though the great majority of the brain's cells are created during fetal development, some areas of the brain continue to produce new neurons during the early years of life. However, until recently, it was thought that neurogenesis - the creation of new brain cells- ceased shortly after the start of our life.
The possibility, that the brain can adapt and remodel itself in response to damage and illness, is provided by the capacity to generate new brain cells.
Adult neurogenesis was long thought to be impossible, but newer evidence indicates that it can occur, at least in certain important brain regions. Studies point to the possibility that brain cells can regrow and regain lost abilities.

Neurogenesis Continues All Life Long

Nevertheless, studies conducted in the past 20 years have revealed that the hippocampus, a region of the brain, may be the source of new brain cells for the duration of an individual's life. According to a study, neurogenesis takes place in the hippocampus's dentate gyrus and new brain cells are still forming as people age. This area of the brain is where new cells are formed, and it helps with memory and learning as well as stress relief.

Ways to Support Neurogenesis

The most important one is age. For example, we know that a large number of the hippocampal neuronal connections will be destroyed by the time many adults reach their 80s. Time stops for no one, but if you maintain an active lifestyle—physically, socially, and mentally—you might be able to preserve your synaptic connections.
1. Work Out Your Body: Exercise has long been seen to be one of the most promising things that can "amp up" this process. Both the number of cells produced in the hippocampus and the amount of genetic information encoded increased with exercise. This indicates that the brain's ability to store information for learning and memory is enhanced in addition to the brain's overall function.
2. Practice in Mental Exercise: Scientists have discovered that enriched environments, in addition to physical activity, can support the survival of aging cells and the generation of new ones. If you engage in mental exercise, you can sustain good brain function to a greater extent.
3. Control Your Anxiety: Furthermore, we are aware that stress—both short-term and long-term—can reduce neurogenesis in the adult brain's hippocampus. Effective stress management can involve a variety of techniques, such as having an optimistic outlook, practicing relaxation techniques, getting enough sleep, and participating in leisure activities. Since every person is unique, it's critical to determine what suits you the best.

What happens to brain cells during an Epileptic Seizure?

Yes, epileptic seizures can lead to brain cell degeneration, particularly if they are frequent, prolonged, or severe. The exact number of brain cells that die during an epileptic seizure can vary widely depending on several factors, including the type, duration, and severity of the seizure, as well as the individual's overall brain health. Generally, most seizures, especially those that are well-controlled or infrequent, do not cause significant or widespread brain cell death. However, prolonged seizures, such as status epilepticus (which lasts longer than 5 minutes or occurs in rapid succession without recovery), can lead to more significant neuronal damage. Here are the main mechanisms and factors involved:

1. Excitotoxicity: Excitatory neurotransmitters such as glutamate are released in excess during an epileptic episode. An excess of calcium ions from these overstimulated neurons may induce cellular harm or even neuronal death.
2. Oxidative Stress: When seizures occur, more reactive oxygen species (ROS) are produced. ROS can cause oxidative stress, which can harm lipids, proteins, and DNA in cells.
3. Energy Depletion: Seizures need a large amount of energy due to their increased electrical activity. The cell's energy currency, ATP, may be exhausted as a result of this increased demand, which could cause damage and malfunction.
4. Inflammation: Seizures can trigger inflammatory responses in the brain. The release of inflammatory mediators like cytokines can contribute to neuronal damage and degeneration.
5. Severity and Duration of Seizures:
       - Status Epilepticus: This is a condition where seizures last longer than five minutes or occur in rapid succession without the individual regaining consciousness between them. Status epilepticus is particularly dangerous and can lead to significant brain injury or cell death.
      - Frequent Seizures: Chronic, recurrent seizures, as seen in poorly controlled epilepsy, can lead to cumulative brain damage over time.
6. Underlying Conditions: The cause of epilepsy itself can contribute to brain cell degeneration. For instance, epilepsy resulting from traumatic brain injury, infections, stroke, or neurodegenerative diseases may involve underlying brain damage that predisposes to further neuronal loss during seizures.
It's important for individuals with epilepsy to work closely with their healthcare providers to manage and control seizures effectively to minimize potential brain damage.

How ayurveda helps stop brain cell degeneration?

It should be crucial to reduce the number of seizures. It can indeed help lessen brain cell death and improve overall quality of life. Some practices and herbs used in Ayurveda have shown promise in preliminary studies. Neeray Epilepsy Clinic provides comprehensive and holistic treatment specifically for epilepsy patients. Our goal is that our patients receive the best care, in accordance with the principles of traditional Ayurvedic medicine and the latest results of modern medicine. Here are a few Ayurvedic approaches that are commonly recommended for supporting brain health:

1. Herbs and Formulations
       - Brahmi (Bacopa monnieri): Known for its neuroprotective properties, Brahmi is believed to enhance cognitive function, reduce anxiety, and improve memory. Some studies suggest it may have antioxidant effects and support neuron health.
      - Ashwagandha (Withania somnifera): Often used for its adaptogenic properties, Ashwagandha may help reduce stress and protect brain cells from oxidative damage. Research indicates it may promote neurogenesis (the growth of new neurons).
       - Turmeric (Curcuma longa): Containing the active compound curcumin, turmeric has strong anti-inflammatory and antioxidant properties. It is thought to help protect brain cells from degeneration and support overall brain health. Our products containing curcumin can help reduce inflammation and support brain functions.
       - Shankhpushpi (Convolvulus pluricaulis): Traditionally used to enhance memory and cognitive function, Shankhpushpi may help reduce oxidative stress and protect neurons.
       - Ginkgo Biloba: While not traditionally an Ayurvedic herb, Ginkgo is sometimes incorporated into Ayurvedic practices due to its potential to improve blood flow to the brain and protect against oxidative damage.

2. Lifestyle Modifications and Practices
      - Stress Management: Techniques such as mindfulness, cognitive-behavioral therapy (CBT), and relaxation exercises to manage stress.
       - Avoiding Triggers: Identifying and avoiding known seizure triggers, such as alcohol, flashing lights, or specific foods.
       - Daily Routine (Dinacharya): Maintaining a consistent daily routine to promote stability and reduce stress.
       - Sleep Hygiene: Adequate sleep is crucial for individuals with epilepsy, as sleep deprivation is a well-known seizure trigger. While the specific amount of sleep needed can vary based on individual needs and circumstances, general recommendations can be made:

General Sleep Recommendations
      - Adults: Typically, adults require 7 to 9 hours of sleep per night. For people with epilepsy, aiming for the higher end of this range is often beneficial.
       - Teenagers (14-17 years old): Teenagers need about 8 to 10 hours of sleep per night.
       - School-Aged Children (6-13 years old): Children in this age group need approximately 9 to 11 hours of sleep per night.
      - Preschoolers (3-5 years old): They require around 10 to 13 hours of sleep per night, including naps.
       - Toddlers (1-2 years old): They typically need 11 to 14 hours of sleep per night, including naps.
       - Infants (4-11 months old): Infants should get 12 to 15 hours of sleep per day, including naps.

Tips for Improving Sleep Quality
      - Consistent Sleep Schedule: Going to bed and waking up at the same time every day, even on weekends, helps regulate the body's internal clock.
      - Sleep Environment: Creating a comfortable sleep environment that is cool, quiet, and dark can enhance sleep quality. Using earplugs, eye masks, or white noise machines if necessary.
      - Pre-Sleep Routine: Establishing a calming pre-sleep routine, such as reading a book, taking a warm bath, or practicing relaxation techniques like deep breathing or meditation.
      - Limiting Stimulants: Avoiding caffeine, nicotine, and heavy meals close to bedtime as they can interfere with sleep.
       - Electronic Devices: Reducing exposure to screens (phones, tablets, computers) at least an hour before bedtime, as the blue light emitted can disrupt the production of melatonin, a hormone that regulates sleep.
       - Physical Activity: Regular physical activity during the day can promote better sleep. However, vigorous exercise close to bedtime should be avoided as it can be stimulating.

3. Meditation and Yoga: Regular practice of meditation and yoga can reduce stress, improve mental clarity, and enhance overall brain function. At our clinic, we recommend regular practice of meditation and yoga, which help reduce stress and improve mental clarity. Techniques like pranayama (breathing exercises) are believed to increase oxygen flow to the brain, promoting neuronal health.

4. Diet: Ayurveda emphasizes a balanced diet that supports overall health, including brain health. This includes consuming foods rich in antioxidants, healthy fats (like those found in nuts and seeds), and anti-inflammatory foods. Come to Neeraj Epilepsy Clinic for a special diet consultation. Our nutrition experts provide personalized dietary advice to our patients. Your diet will prepare according to the principles of Ayurveda, helps restore the body's balance and optimize brain functions.

5. Ayurvedic Therapies
       - Abhyanga (Oil Massage): Regular oil massage, especially with oils like sesame or Brahmi oil, is believed to nourish the nervous system and promote relaxation and mental clarity. Our clinic performs Abhyanga treatments with special oils to support the overall well-being of our patients.
       - Rasayana Therapy: This is a rejuvenation therapy aimed at promoting longevity and preventing degeneration. It includes specific diets, herbal preparations, and lifestyle practices designed to enhance vitality and health.

6. Detoxification
       - Panchakarma: A detoxification process that involves five procedures to cleanse the body of toxins. This holistic approach is believed to balance the doshas (body energies) and improve overall health, including brain function.

7. Integrated Approach and Monitoring
       - Collaboration with Healthcare Providers:
             -It's important to maintain an open line of communication with both conventional healthcare providers and Ayurvedic practitioners to ensure a cohesive and safe treatment plan.
       - Regular Monitoring and Follow-Up:
              - Regular check-ups to monitor seizure frequency, medication side effects, and overall health.
              - Adjustments to the treatment plan based on the individual's response and any new developments.
       - Personalized Treatment Plan: Personalized approaches based on the individual's unique constitution (Prakriti) and specific characteristics of their condition (Vikriti) are central to Ayurvedic treatment.

Ayurveda offers a holistic approach to supporting brain health and potentially preventing brain cell degeneration. However, it is important to approach these treatments with an open mind and consider them as complementary to conventional medical treatments. Consulting with healthcare professionals who have knowledge of both modern medicine and Ayurveda can help create a balanced and effective health plan.

Our clinic works with a team of highly qualified and experienced Ayurvedic doctors, dieticians and yoga instructors. We are all committed to providing the best care and support to our patients. Visit us and discover how Ayurveda can help you treat epilepsy and improve your quality of life!